The O'Brien Institute (OBI) was established in 1970 to promote research and training in microsurgery. Historically, research from OBI led the way in clinical and experimental research in microsurgery. Initially known as the Microsurgery Research Centre, it quickly developed a pre-eminent reputation and attracted plastic and orthopaedic surgeons from the US, UK, Europe, Japan and elsewhere and many of these researchers have returned to their home countries to become leaders in the field. More than 200 surgically trained researchers have completed Fellowships since 1972.

Nowadays, the OBI Department conducts internationally recognised scientific research into clinical problems typically treated by plastic surgeons. These problems include impaired healing and deficits of soft tissue or tissue injury following trauma, cancer treatment or congenital deformity. The Department is configured into separate laboratories according to the specific field of research and expertise under the guidance of the Director. PhD, Doctorate, Masters and B.Sc(Hons) students are an integral part of our program. Overseas and Australian Surgical Research Fellowships have also been a key feature of the Institute. We also welcome shorter term visiting clinicians who come here to learn about the exacting work of microsurgery.