04b_03_02 Pharmacokinetic,Pharmacodynamic and Pharmacogenomic Differences Between Adults and Children

Pharmacokinetic Pharmacodynamic and Pharmacogenomic Differences Between Adults and Children
Session Overview
Description
This session will provide an overview of pharmacokinetic (PK) maturation during infancy and the use of size models to describe PK differences between children and adults. It will go on to describe known pharmacodynamic (PD) differences and consider the impact of pharmacogenomic (PG) differences in infancy.

Learning Objectives
By the end of this session you will be able to:

• Describe the impact of size, maturation of enzyme systems, altered volume of distribution, protein binding and absorption changes on PK changes with age
• List and describe limited reported PD age-related changes
• Assess the impact of pharmacogenomics at different ages

Prerequisites
Before commencing this session you should have:

• Completed sessions on Pharmacology