This course covers the statutory and mandatory training for Safeguarding Children Level 2. It has been designed to meet the learning outcomes in the UK Core Skills Training Framework.
This session will develop the three compartment model to include an effect-site and discuss its application to target-controlled infusions used for induction and maintenance of anaesthesia. The concept of context-sensitive half-time will be introduced.
This session will develop pharmacokinetic modelling. The two- and three-compartment models will be introduced showing how the parameters described in a simple model are used in these more complicated models.
This session will introduce pharmacokinetics and modelling. The simple one-compartment model will be described and reasons presented as to why such a model rarely describes drug behaviour.
This session introduces the cytochrome P450 enzyme system and its role in physiology and pharmacology, with a focus on the effects of drugs used commonly in anaesthesia.
This session describes the processes of metabolism (biotransformation) of drugs within the human body, where these processes occur, and factors that influence them. The session also gives clinical examples of these processes that are relevant to the anaes
This session discusses the pharmacokinetic process of elimination, which includes excretion and metabolism (biotransformation). It also discusses the kinetics of elimination and pathways of biotransformation, including the factors influencing it.
This session describes the physicochemical properties of the inhaled anaesthetic drugs and how they affect the onset, maintenance and offset of anaesthesia. We will compare volatile anaesthetic agents using these properties. The session also describes the
